Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies
نویسندگان
چکیده
منابع مشابه
Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies.
Retinal dystrophies are predominantly caused by mutations affecting the visual phototransduction system and cilia, with few genes identified that function to maintain photoreceptor survival. We reasoned that growth factors involved with early embryonic retinal development would represent excellent candidates for such diseases. Here we show that mutations in the transforming growth factor-β (TGF...
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ژورنال
عنوان ژورنال: Human Molecular Genetics
سال: 2013
ISSN: 1460-2083,0964-6906
DOI: 10.1093/hmg/dds560